BAIT
CEBPD
C/EBP-delta, CELF, CRP3, NF-IL6-beta
CCAAT/enhancer binding protein (C/EBP), delta
GO Process (1)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
PREY
XPO1
CRM1, emb, exp1
exportin 1
GO Process (12)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- gene expression [TAS]
- intracellular transport of virus [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- protein export from nucleus [IMP]
- ribosomal large subunit export from nucleus [IMP]
- ribosomal small subunit export from nucleus [IMP]
- transforming growth factor beta receptor signaling pathway [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.
Maintenance of genomic integrity is an essential cellular function. We previously reported that the transcription factor and tumor suppressor CCAAT/enhancer binding protein δ (C/EBPδ, CEBPD; also known as "NFIL-6β") promotes genomic stability. However, the molecular mechanism was not known. Here, we show that C/EBPδ is a DNA damage-induced gene, which supports survival of mouse bone marrow cells, mouse embryo fibroblasts ... [more]
Proc. Natl. Acad. Sci. U.S.A. Sep. 14, 2010; 107(37);16131-6 [Pubmed: 20805509]
Throughput
- Low Throughput
Curated By
- BioGRID