BAIT
ABCB1
ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DHX9
DDX9, LKP, NDH2, NDHII, RHA
DEAH (Asp-Glu-Ala-His) box helicase 9
GO Process (10)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- ATP catabolic process [IBA, TAS]
- CRD-mediated mRNA stabilization [IMP]
- DNA duplex unwinding [TAS]
- RNA processing [IBA]
- RNA splicing [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- mRNA splicing, via spliceosome [TAS]
- osteoblast differentiation [IDA]
- positive regulation of type I interferon production [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.
RNA helicase A (RHA) is a member of the DEAD/H family of RNA helicases and unwinds duplex RNA and DNA. Recent studies have shown that RHA regulates the activity of gene promoters. However, little information is available about the in vivo relevance of RHA in the regulation of natural genes. We previously characterized a nuclear protein (MEF1) that binds to ... [more]
J. Biol. Chem. Apr. 23, 2004; 279(17);17134-41 [Pubmed: 14769796]
Throughput
- Low Throughput
Curated By
- BioGRID