BAIT

BAZ1A

ACF1, WALp1, WCRF180, hACF1, HSPC317
bromodomain adjacent to zinc finger domain, 1A
GO Process (4)
GO Function (2)
GO Component (2)
Homo sapiens
PREY

CHRAC1

CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1
chromatin accessibility complex 1
GO Process (2)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The histone-fold protein complex CHRAC-15/17 enhances nucleosome sliding and assembly mediated by ACF.

Kukimoto I, Elderkin S, Grimaldi M, Oelgeschlaeger T, Varga-Weisz PD

The histone fold is a structural motif with which two related proteins interact and is found in complexes involved in wrapping DNA, the nucleosome, and transcriptional regulation, as in NC2. We reveal a novel function for histone-fold proteins: facilitation of nucleosome remodeling. ACF1-ISWI complex (ATP-dependent chromatin assembly and remodeling factor [ACF]) associates with histone-fold proteins (CHRAC-15 and CHRAC-17 in the ... [more]

Mol. Cell Jan. 30, 2004; 13(2);265-77 [Pubmed: 14759371]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
BAZ1A CHRAC1
Positive Genetic
Positive Genetic

Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a less severe fitness defect than expected under a given condition. This term is reserved for high or low throughput studies with scores.

High3.292BioGRID
2539556
CHRAC1 BAZ1A
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID