BAIT
EZH1
KMT6B
enhancer of zeste 1 polycomb repressive complex 2 subunit
GO Process (1)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ESC
CG14941, Dmel\CG14941, L41867, dESC, sc, Dmel_CG14941
extra sexcombs
GO Process (8)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The Drosophila esc and E(z) proteins are direct partners in polycomb group-mediated repression.
The extra sex combs (esc) and Enhancer of zeste [E(z)] proteins are members of the Drosophila Polycomb group (Pc-G) of transcriptional repressors. Here we present evidence for direct physical interaction between the esc and E(z) proteins using yeast two-hybrid and in vitro binding assays. In addition, coimmunoprecipitation from embryo extracts demonstrates association of esc and E(z) in vivo. We have ... [more]
Mol. Cell. Biol. May. 01, 1998; 18(5);2825-34 [Pubmed: 9566901]
Throughput
- Low Throughput
Curated By
- BioGRID