PREY

NT5C2

2010002I23Rik, CnII, ENSMUSG00000025039, Gm9751, Gmp, Nt5b, Pnt5, cN-II
5'-nucleotidase, cytosolic II
GO Process (3)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.

Mallette FA, Calabrese V, Ilangumaran S, Ferbeyre G

Members of the signal transducers and activators of transcription (STATs) family of proteins, which connect cytokine signaling to activation of transcription, are frequently activated in human cancers. Suppressors of cytokine signaling (SOCS) are transcriptional targets of activated STAT proteins that negatively control STAT signaling. SOCS1 expression is silenced in multiple human cancers suggesting a tumor suppressor role for this protein. ... [more]

Aging (Albany NY) Jul. 01, 2010; 2(7);445-52 [Pubmed: 20622265]

Throughput

  • Low Throughput

Curated By

  • BioGRID