Protein SUP-26
GO Process (3)
GO Function (2)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Caenorhabditis elegans

Reconstituted Complex

An interaction is detected between purified proteins in vitro.


Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation.

Mapes J, Chen JT, Yu JS, Xue D

Translational repression mediated by RNA-binding proteins or micro RNAs has emerged as a major regulatory mechanism for fine-tuning important biological processes. In Caenorhabditis elegans, translational repression of the key sex-determination gene tra-2 (tra, transformer) is controlled by a 28-nucleotide repeat element, the TRA-2/GLI element (TGE), located in its 3' untranslated region (UTR). Mutations that disrupt TGE or the germline-specific TGE-binding ... [more]

Proc. Natl. Acad. Sci. U.S.A. Oct. 19, 2010; 107(42);18022-7 [Pubmed: 20921392]


  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SUP-26 PAB-1
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.


Curated By

  • BioGRID