BAIT
SUP-26
CELE_R10E4.2
Protein SUP-26
GO Process (3)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Caenorhabditis elegans
PREY
TRA-2
CELE_C15F1.3
Protein TRA-2
GO Process (8)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Caenorhabditis elegans
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation.
Translational repression mediated by RNA-binding proteins or micro RNAs has emerged as a major regulatory mechanism for fine-tuning important biological processes. In Caenorhabditis elegans, translational repression of the key sex-determination gene tra-2 (tra, transformer) is controlled by a 28-nucleotide repeat element, the TRA-2/GLI element (TGE), located in its 3' untranslated region (UTR). Mutations that disrupt TGE or the germline-specific TGE-binding ... [more]
Proc. Natl. Acad. Sci. U.S.A. Oct. 19, 2010; 107(42);18022-7 [Pubmed: 20921392]
Throughput
- Low Throughput
Curated By
- BioGRID