An interaction is detected between and protein and an RNA in vitro.


Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation.

Mapes J, Chen JT, Yu JS, Xue D

Translational repression mediated by RNA-binding proteins or micro RNAs has emerged as a major regulatory mechanism for fine-tuning important biological processes. In Caenorhabditis elegans, translational repression of the key sex-determination gene tra-2 (tra, transformer) is controlled by a 28-nucleotide repeat element, the TRA-2/GLI element (TGE), located in its 3' untranslated region (UTR). Mutations that disrupt TGE or the germline-specific TGE-binding ... [more]

Proc. Natl. Acad. Sci. U.S.A. Oct. 19, 2010; 107(42);18022-7 [Pubmed: 20921392]


  • Low Throughput

Curated By

  • BioGRID