BAIT

MYOD1

MYF3, MYOD, PUM, bHLHc1
myogenic differentiation 1
Homo sapiens
PREY

BHLHE40

BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14
basic helix-loop-helix family, member e40
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements.

Fujimoto K, Hamaguchi H, Hashiba T, Nakamura T, Kawamoto T, Sato F, Noshiro M, Bhawal UK, Suardita K, Kato Y

Dec2, a member of the basic helix-loop-helix (bHLH) superfamily, has been shown to function as a transcriptional repressor and is implicated in cell proliferation and differentiation. In addition, Dec2 transcripts exhibit a striking circadian oscillation in the suprachiasmatic nucleus. To identify the molecular mechanisms by which Dec2 regulates gene expression, we carried out structure-function analyses. Gel retardation and luciferase assays ... [more]

Int. J. Mol. Med. Jun. 01, 2007; 19(6);925-32 [Pubmed: 17487425]

Throughput

  • Low Throughput

Curated By

  • BioGRID