HCF
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SIN3A
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- determination of adult lifespan [IMP]
- epithelial cell migration [IMP]
- muscle organ development [IMP]
- negative regulation of Wnt signaling pathway [IGI]
- negative regulation of epithelial cell migration [IGI]
- negative regulation of transcription, DNA-templated [IEP, IMP, TAS]
- neuron development [IMP]
- peripheral nervous system development [TAS]
- regulation of hemocyte proliferation [IMP]
- regulation of mitotic cell cycle [IMP]
- regulation of protein stability [IMP]
- regulation of transcription, DNA-templated [ISS]
- wing disc development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Functional dissection of the ash2 and ash1 transcriptomes provides insights into the transcriptional basis of wing phenotypes and reveals conserved protein interactions.
The trithorax group (trxG) genes absent, small or homeotic discs 1 (ash1) and 2 (ash2) were isolated in a screen for mutants with abnormal imaginal discs. Mutations in either gene cause homeotic transformations but Hox genes are not their only targets. Although analysis of double mutants revealed that ash2 and ash1 mutations enhance each other's phenotypes, suggesting they are functionally ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SIN3A HCF | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - |
Curated By
- BioGRID