BAIT

LRIF1

C1orf103, RIF1, RP11-96K19.1
ligand dependent nuclear receptor interacting factor 1
GO Process (0)
GO Function (1)
GO Component (3)

Gene Ontology Molecular Function

Homo sapiens
PREY

RARA

NR1B1, RAR
retinoic acid receptor, alpha
GO Process (24)
GO Function (15)
GO Component (6)
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

RIF-1, a novel nuclear receptor corepressor that associates with the nuclear matrix.

Li HJ, Haque ZK, Chen A, Mendelsohn M

The retinoic acid receptors (RARs) are ligand-dependent transcription factors that play critical roles in cell differentiation, embryonic development, and tumor suppression. RAR transcriptional activities are mediated by a growing family of nuclear receptor (NR) coregulators. Here we report the cloning and characterization of a novel protein RIF1 (receptor interacting factor) that interacts with RARalpha in vivo and in vitro. RIF1 ... [more]

J. Cell. Biochem. Nov. 01, 2007; 102(4);1021-35 [Pubmed: 17455211]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
RARA LRIF1
Far Western
Far Western

An interaction is detected between a protein immobilized on a membrane and a purified protein probe.

Low-BioGRID
-
RARA LRIF1
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID