arp10, SPAC6G9.07c
ARP2/3 actin-organizing complex subunit Arc4
GO Process (3)
GO Function (0)
GO Component (4)
Schizosaccharomyces pombe (972h)


Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.


Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis.

Cabrera R, Suo J, Young E, Chang EC

We characterized the Schizosaccharomyces pombe arc3 gene, whose product shares sequence homology with that of the budding yeast ARC18 and human ARPC3/p21 subunits of the Arp2/3 complex. Our data showed that Arc3p co-localizes with F-actin patches at the cell ends, but not with F-actin cables or the equatorial actin ring, and binds other subunits of the Arp2/3 complex. Gene deletion ... [more]

Unknown Mar. 01, 2011; 0(0); [Pubmed: 21449051]


  • Low Throughput

Curated By

  • BioGRID