BAIT
ARC3
arc21, SPBC1778.08c
ARP2/3 actin-organizing complex subunit Arc21
GO Process (5)
GO Function (0)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
ARC4
arp10, SPAC6G9.07c
ARP2/3 actin-organizing complex subunit Arc4
GO Process (3)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis.
We characterized the Schizosaccharomyces pombe arc3 gene, whose product shares sequence homology with that of the budding yeast ARC18 and human ARPC3/p21 subunits of the Arp2/3 complex. Our data showed that Arc3p co-localizes with F-actin patches at the cell ends, but not with F-actin cables or the equatorial actin ring, and binds other subunits of the Arp2/3 complex. Gene deletion ... [more]
Unknown Mar. 01, 2011; 0(0); [Pubmed: 21449051]
Throughput
- Low Throughput
Curated By
- BioGRID