BAIT
ADNP
ADNP1, MRD28
activity-dependent neuroprotector homeobox
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
ARID1A
B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1, RP1-50O24.1
AT rich interactive domain 1A (SWI-like)
GO Process (9)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- androgen receptor signaling pathway [IDA]
- chromatin remodeling [IDA]
- chromatin-mediated maintenance of transcription [TAS]
- glucocorticoid receptor signaling pathway [IDA]
- intracellular estrogen receptor signaling pathway [IDA]
- nucleosome disassembly [IDA]
- nucleosome mobilization [TAS]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of transcription from RNA polymerase II promoter [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex.
Complete deficiency in activity-dependent neuroprotective protein (ADNP), a heterochromatin 1-binding protein, results in dramatic changes in gene expression, neural tube closure defects, and death at gestation day 9 in mice. To further understand the cellular roles played by ADNP, the HEK293 human embryonic kidney cell line that allows efficient transfection with recombinant DNA was used as a model for the ... [more]
J. Biol. Chem. Nov. 23, 2007; 282(47);34448-56 [Pubmed: 17878164]
Throughput
- Low Throughput
Curated By
- BioGRID