PREY

BLM

BS, RECQ2, RECQL2, RECQL3
Bloom syndrome, RecQ helicase-like
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K

PTIP, a protein with tandem BRCT domains, has been implicated in DNA damage response. However, its normal cellular functions remain unclear. Here we show that while ectopically expressed PTIP is capable of interacting with DNA damage response proteins including 53BP1, endogenous PTIP, and a novel protein PA1 are both components of a Set1-like histone methyltransferase (HMT) complex that also contains ... [more]

J. Biol. Chem. Jul. 13, 2007; 282(28);20395-406 [Pubmed: 17500065]

Throughput

  • Low Throughput

Curated By

  • BioGRID