PTPRQ
Gene Ontology Biological Process
Gene Ontology Cellular Component
CDH2
Gene Ontology Biological Process
- blood vessel morphogenesis [IMP]
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [IDA, ISO]
- cell adhesion [IDA]
- cell migration [IDA]
- cell-cell adhesion mediated by cadherin [IDA]
- glial cell differentiation [IDA]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [IDA]
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- negative regulation of canonical Wnt signaling pathway [IGI]
- neuronal stem cell maintenance [IDA]
- positive regulation of MAPK cascade [IGI]
- protein heterooligomerization [ISO]
- regulation of Rho protein signal transduction [ISO]
- regulation of axonogenesis [ISO]
- regulation of myelination [ISO]
- regulation of protein localization [ISO]
- single organismal cell-cell adhesion [ISO]
- striated muscle cell differentiation [IGI]
- synapse assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- adherens junction [IDA]
- apical plasma membrane [IDA]
- catenin complex [ISO]
- cell-cell adherens junction [ISO]
- cell-cell junction [IDA, ISO]
- extracellular vesicular exosome [ISO]
- fascia adherens [IDA, ISO]
- focal adhesion [ISO]
- intercalated disc [IDA, ISO]
- lamellipodium [IDA]
- membrane [ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- synapse [IDA, ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).
Receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT) is a transmembrane protein that is highly expressed in the developing and adult central nervous system. It is a member of the RPTP R2B subfamily, which includes PTPkappa, PTPmu and PCP-2. Glutathione-S-transferase (GST) pulldown assays were used to show that RPTPrho interacts with several adherens junctional proteins in brain, including E-cadherin, N-cadherin, VE-cadherin (cadherin-5), ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID