PCP2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ACTN1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA]
- cell projection [ISO]
- cortical actin cytoskeleton [ISO]
- cortical cytoskeleton [TAS]
- cytoplasm [ISO]
- dendritic spine [ISO]
- dense core granule membrane [TAS]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- fascia adherens [IDA]
- focal adhesion [ISO, TAS]
- nucleus [ISO]
- secretory granule [NAS]
- stress fiber [IDA, ISO, TAS]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).
Receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT) is a transmembrane protein that is highly expressed in the developing and adult central nervous system. It is a member of the RPTP R2B subfamily, which includes PTPkappa, PTPmu and PCP-2. Glutathione-S-transferase (GST) pulldown assays were used to show that RPTPrho interacts with several adherens junctional proteins in brain, including E-cadherin, N-cadherin, VE-cadherin (cadherin-5), ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID