CSNK2B
Gene Ontology Biological Process
- I-kappaB kinase/NF-kappaB signaling [TAS]
- adiponectin-activated signaling pathway [ISO]
- endothelial tube morphogenesis [ISO]
- negative regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of Wnt signaling pathway [TAS]
- positive regulation of activin receptor signaling pathway [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CBX2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H3.
The chromatin organizer modifier domain (chromodomain) is present in proteins that contribute to chromatin organization and mediates their binding to methylated histone H3. Despite a high level of sequence conservation, individual chromodomains manifest substantial differences in binding preference for methylated forms of histone H3, suggesting that posttranslational modification of the chromodomain might be an important determinant of binding specificity. We ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID