SMARCA4
Gene Ontology Biological Process
- ATP catabolic process [IGI]
- ATP-dependent chromatin remodeling [IDA]
- chromatin remodeling [IC, IDA]
- negative regulation of G1/S transition of mitotic cell cycle [TAS]
- negative regulation of androgen receptor signaling pathway [IMP]
- negative regulation of cell growth [IMP]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription from RNA polymerase II promoter during mitosis [TAS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- neural retina development [IEP]
- nucleosome disassembly [IDA]
- positive regulation by host of viral transcription [IMP]
- positive regulation of Wnt signaling pathway [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
Gene Ontology Molecular Function- DNA polymerase binding [IPI]
- DNA-dependent ATPase activity [IGI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- Tat protein binding [IPI]
- androgen receptor binding [IPI]
- lysine-acetylated histone binding [IDA]
- nucleosomal DNA binding [IDA]
- p53 binding [IPI]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- transcription coactivator activity [IMP, NAS]
- transcription corepressor activity [IDA]
- DNA polymerase binding [IPI]
- DNA-dependent ATPase activity [IGI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- Tat protein binding [IPI]
- androgen receptor binding [IPI]
- lysine-acetylated histone binding [IDA]
- nucleosomal DNA binding [IDA]
- p53 binding [IPI]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- transcription coactivator activity [IMP, NAS]
- transcription corepressor activity [IDA]
Gene Ontology Cellular Component
KPNA2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
The SWI/SNF chromatin remodeling complex plays pivotal roles in mammalian transcriptional regulation. In this study, we identify the human requiem protein (REQ/DPF2) as an adaptor molecule that links the NF-kappaB and SWI/SNF chromatin remodeling factor. Through in vitro binding experiments, REQ was found to bind to several SWI/SNF complex subunits and also to the p52 NF-kappaB subunit through its nuclear ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SMARCA4 KPNA2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3370053 | |
| KPNA2 SMARCA4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9506 | BioGRID | 3126932 |
Curated By
- BioGRID