AT5G53360
Gene Ontology Biological Process
LHY
Gene Ontology Biological Process
- circadian rhythm [IGI]
- long-day photoperiodism, flowering [IGI]
- negative regulation of circadian rhythm [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IMP]
- regulation of circadian rhythm [IMP]
- regulation of transcription, DNA-templated [TAS]
- response to abscisic acid [IEP]
- response to auxin [IEP]
- response to cadmium ion [IEP]
- response to cold [IGI]
- response to ethylene [IEP]
- response to gibberellin [IEP]
- response to jasmonic acid [IEP]
- response to salicylic acid [IEP]
- response to salt stress [IEP]
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Ubiquitination of LHY by SINAT5 regulates flowering time and is inhibited by DET1.
Ubiquitin is a small polypeptide and ubiquitination is the post-translational modification by ubiquitin protein, resulting in degradation of target proteins by the 26S proteasome complex. Here, we found that E3 ubiquitin ligase SINAT5, an Arabidopsis homologue of the Drosophila SINA RING-finger protein, interacts directly with LHY, a component of the circadian oscillator, and DET1, a negative regulator of light-regulated gene ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AT5G53360 LHY | Biochemical Activity Biochemical Activity An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation. | Low | - | BioGRID | 532121 |
Curated By
- BioGRID