BAIT
LMNA
Dhe
lamin A
GO Process (13)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
- establishment of cell polarity [NAS]
- establishment or maintenance of microtubule cytoskeleton polarity [IMP]
- muscle organ development [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [IMP]
- negative regulation of release of cytochrome c from mitochondria [IMP]
- nuclear envelope organization [IGI]
- nucleus organization [IMP]
- positive regulation of cell aging [ISO]
- protein localization to nucleus [IMP]
- regulation of cell migration [IMP]
- regulation of protein localization to nucleus [IMP]
- sterol regulatory element binding protein import into nucleus [IMP]
- ventricular cardiac muscle cell development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB5A
2410015H04Rik, AI663973, AU021172, nnyRab5a
RAB5A, member RAS oncogene family
GO Process (16)
GO Function (6)
GO Component (26)
Gene Ontology Biological Process
- GTP catabolic process [IDA, ISO]
- Rab protein signal transduction [IBA]
- early endosome to late endosome transport [ISO]
- endocytosis [IDA, ISO]
- endosome organization [ISO]
- intracellular protein transport [IBA]
- positive regulation of exocytosis [ISO]
- positive regulation of smooth muscle cell migration [ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- receptor internalization involved in canonical Wnt signaling pathway [ISO]
- regulation of endocytosis [IBA]
- regulation of endosome size [ISO]
- regulation of filopodium assembly [IBA, ISO]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of synaptic vesicle exocytosis [ISO]
- synaptic vesicle recycling [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [IDA]
- axon [ISO]
- axon terminus [ISO]
- cell [IBA]
- cytoplasm [IDA, ISO]
- cytoplasmic side of early endosome membrane [ISO]
- cytosol [ISO]
- dendrite [ISO]
- early endosome [IDA, ISO]
- endocytic vesicle [IDA]
- endosome [IDA, ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IBA]
- membrane raft [IDA]
- neuron projection [ISO]
- neuronal cell body [ISO]
- perinuclear region of cytoplasm [ISO]
- phagocytic vesicle [IDA]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- recycling endosome [ISO]
- ruffle [IDA]
- somatodendritic compartment [ISO]
- synaptic vesicle [ISO]
- terminal bouton [ISO]
- zymogen granule membrane [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of differential protein interactors of lamin A and progerin.
The nuclear lamina is an interconnected meshwork of intermediate filament proteins underlying the nuclear envelope. The lamina is an important regulator of nuclear structural integrity as well as nuclear processes, including transcription, DNA replication and chromatin remodeling. The major components of the lamina are A- and B-type lamins. Mutations in lamins impair lamina functions and cause a set of highly ... [more]
Unknown Dec. 01, 2009; 1(6);513-525 [Pubmed: 21327095]
Throughput
- Low Throughput
Curated By
- BioGRID