TACR1
Gene Ontology Biological Process
- acute inflammatory response [IEP]
- aggressive behavior [IMP]
- angiotensin-mediated drinking behavior [IMP]
- associative learning [IMP]
- behavioral response to pain [IMP]
- eating behavior [IMP]
- learning or memory [IMP]
- long-term memory [IMP]
- neuropeptide signaling pathway [TAS]
- operant conditioning [IMP]
- positive regulation of action potential [IMP]
- positive regulation of blood pressure [IMP]
- positive regulation of cytosolic calcium ion concentration [IMP]
- positive regulation of epithelial cell migration [IMP]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of hormone secretion [IMP]
- positive regulation of leukocyte migration [IMP]
- positive regulation of lymphocyte proliferation [IMP]
- positive regulation of ossification [IMP]
- positive regulation of renal sodium excretion [IMP]
- positive regulation of saliva secretion [IMP]
- positive regulation of stress fiber assembly [IMP]
- positive regulation of synaptic transmission, GABAergic [IMP]
- positive regulation of synaptic transmission, cholinergic [IMP]
- positive regulation of uterine smooth muscle contraction [IDA]
- positive regulation of vascular permeability [IMP]
- positive regulation of vasoconstriction [IMP]
- regulation of blood pressure [IMP]
- regulation of smooth muscle cell migration [IMP]
- regulation of smooth muscle cell proliferation [IMP]
- response to auditory stimulus [IDA]
- response to electrical stimulus [IEP]
- response to estradiol [IEP]
- response to ethanol [IMP]
- response to heat [IMP]
- response to hormone [IMP]
- response to morphine [IEP]
- response to nicotine [IMP]
- response to organic cyclic compound [IDA]
- response to ozone [IMP]
- response to pain [ISO]
- response to progesterone [IEP]
- sensory perception of pain [IMP, TAS]
- smooth muscle contraction involved in micturition [IMP]
- sperm ejaculation [IMP]
- tachykinin receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Ubiquitin-dependent down-regulation of the neurokinin-1 receptor.
Transient stimulation with substance P (SP) induces endocytosis and recycling of the neurokinin-1 receptor (NK(1)R). The effects of sustained stimulation by high concentrations of SP on NK(1)R trafficking and Ca(2+) signaling, as may occur during chronic inflammation and pain, are unknown. Chronic exposure to SP (100 nm, 3 h) completely desensitized Ca(2+) signaling by wild-type NK(1)R (NK(1)Rwt). Resensitization occurred after ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID