AHR
Gene Ontology Biological Process
- B cell homeostasis [ISO]
- T cell homeostasis [ISO]
- apoptotic process [TAS]
- blood circulation [ISO]
- blood vessel development [ISO]
- blood vessel morphogenesis [ISO]
- blood vessel remodeling [ISO]
- camera-type eye development [ISO]
- cardiac left ventricle morphogenesis [ISO]
- cell morphogenesis [ISO]
- cellular response to cAMP [ISO]
- cellular response to glucocorticoid stimulus [IEP]
- circadian regulation of gene expression [ISO, ISS]
- circumferential growth involved in left ventricle morphogenesis [ISO]
- common bile duct development [ISO]
- embryonic hemopoiesis [ISO]
- gland development [ISO]
- glomerulus morphogenesis [ISO]
- immune system process [ISO]
- intracellular receptor signaling pathway [IDA, ISO, TAS]
- kidney morphogenesis [ISO]
- liver development [ISO]
- lymphocyte homeostasis [ISO]
- negative regulation of necrotic cell death [ISO]
- negative regulation of systemic arterial blood pressure [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO, ISS]
- negative regulation of vasoconstriction [ISO]
- ovarian follicle development [IMP]
- patterning of blood vessels [ISO]
- positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [ISO]
- positive regulation of cell size [ISO]
- positive regulation of growth [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA]
- positive regulation of transcription, DNA-templated [ISO, ISS]
- post-embryonic hemopoiesis [ISO]
- prostate gland development [ISO]
- regulation of B cell proliferation [ISO]
- regulation of blood vessel size [ISO]
- regulation of gene expression [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription, DNA-templated [IDA, ISO]
- reproductive structure development [ISO]
- response to estradiol [IEP]
- response to organic cyclic compound [IEP, IMP]
- response to toxic substance [ISO]
- response to xenobiotic stimulus [IDA, ISO, TAS]
- smooth muscle tissue development [ISO]
- spleen development [ISO]
- transcription from RNA polymerase II promoter [IDA, ISO]
- venous blood vessel development [ISO]
Gene Ontology Molecular Function- DNA binding [ISO, TAS]
- E-box binding [ISO, ISS]
- Hsp90 protein binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- aryl hydrocarbon receptor activity [IDA, TAS]
- enhancer binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [ISO, TAS]
- E-box binding [ISO, ISS]
- Hsp90 protein binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- aryl hydrocarbon receptor activity [IDA, TAS]
- enhancer binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Rats fed soy protein isolate (SPI) have impaired hepatic CYP1A1 induction by polycyclic aromatic hydrocarbons as a result of interference with aryl hydrocarbon receptor signaling.
Consumption of soy diets has been found to reduce cancer incidence in animals and is associated with reduced cancer risk in humans. Previously, we have demonstrated that female Sprague-Dawley rats fed purified AIN-93G diets with soy protein isolate (SPI) as the sole protein source had reduced CYP1A1 induction and basal aryl hydrocarbon receptor (AhR) levels relative to those fed the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID