BAIT
KAT5
ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2
K(lysine) acetyltransferase 5
GO Process (13)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IDA]
- androgen receptor signaling pathway [NAS]
- cellular response to estradiol stimulus [IDA]
- chromatin organization [TAS]
- double-strand break repair [IMP]
- histone acetylation [IDA]
- negative regulation of interleukin-2 production [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA, NAS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- response to ionizing radiation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HDGF
HMG1L2, RP11-66D17.10-003
hepatoma-derived growth factor
GO Process (6)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cell proliferation [TAS]
- cellular protein metabolic process [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- signal transduction [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.
c-Myc (Myc) is an important transcriptional regulator in embryonic stem (ES) cells, somatic cell reprogramming, and cancer. Here, we identify a Myc-centered regulatory network in ES cells by combining protein-protein and protein-DNA interaction studies and show that Myc interacts with the NuA4 complex, a regulator of ES cell identity. In combination with regulatory network information, we define three ES cell ... [more]
Cell Oct. 15, 2010; 143(2);313-24 [Pubmed: 20946988]
Throughput
- Low Throughput
Curated By
- BioGRID