PREY

MAPK8IP3

JIP3, JSAP1, SYD2, syd, AC012180.8
mitogen-activated protein kinase 8 interacting protein 3
GO Process (3)
GO Function (4)
GO Component (2)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, Cantor AB, Orkin SH

c-Myc (Myc) is an important transcriptional regulator in embryonic stem (ES) cells, somatic cell reprogramming, and cancer. Here, we identify a Myc-centered regulatory network in ES cells by combining protein-protein and protein-DNA interaction studies and show that Myc interacts with the NuA4 complex, a regulator of ES cell identity. In combination with regulatory network information, we define three ES cell ... [more]

Cell Oct. 15, 2010; 143(2);313-24 [Pubmed: 20946988]

Throughput

  • Low Throughput

Curated By

  • BioGRID