BAIT
WDR1
Aip1, D5Wsu185e, rede
WD repeat domain 1
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RUVBL2
mp47, p47
RuvB-like protein 2
GO Process (12)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- cellular response to UV [ISO]
- cellular response to estradiol stimulus [ISO]
- chromatin remodeling [ISO]
- establishment of protein localization to chromatin [ISO]
- histone H2A acetylation [ISO]
- histone H4 acetylation [ISO]
- negative regulation of estrogen receptor binding [ISO]
- positive regulation of histone acetylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- transcriptional activation by promoter-enhancer looping [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Pluripotent embryonic stem cells (ESCs) maintain self-renewal while ensuring a rapid response to differentiation cues. The identification of genes maintaining ESC identity is important to develop these cells for their potential therapeutic use. Here we report a genome-scale RNAi screen for a global survey of genes affecting ESC identity via alteration of Oct4 expression. Factors with the strongest effect on ... [more]
Cell Stem Cell May. 08, 2009; 4(5);403-15 [Pubmed: 19345177]
Throughput
- Low Throughput
Curated By
- BioGRID