BAIT
WDR1
Aip1, D5Wsu185e, rede
WD repeat domain 1
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RUVBL1
2510009G06Rik, Pontin52, Tip49a
RuvB-like protein 1
GO Process (6)
GO Function (2)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- Ino80 complex [ISO]
- MLL1 complex [ISO]
- NuA4 histone acetyltransferase complex [ISO]
- Swr1 complex [ISO]
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- intracellular membrane-bounded organelle [ISO]
- nuclear matrix [ISO]
- nucleoplasm [ISO]
- nucleus [ISO]
- protein complex [ISO]
- ribonucleoprotein complex [IDA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Pluripotent embryonic stem cells (ESCs) maintain self-renewal while ensuring a rapid response to differentiation cues. The identification of genes maintaining ESC identity is important to develop these cells for their potential therapeutic use. Here we report a genome-scale RNAi screen for a global survey of genes affecting ESC identity via alteration of Oct4 expression. Factors with the strongest effect on ... [more]
Cell Stem Cell May. 08, 2009; 4(5);403-15 [Pubmed: 19345177]
Throughput
- Low Throughput
Curated By
- BioGRID