PCGF2
Gene Ontology Biological Process
- anterior/posterior pattern specification [IGI, IMP]
- cellular response to hydrogen peroxide [IDA]
- embryonic skeletal system development [IGI]
- embryonic skeletal system morphogenesis [IGI]
- histone acetylation [IGI]
- in utero embryonic development [IGI]
- negative regulation of apoptotic signaling pathway [IGI]
- negative regulation of transcription from RNA polymerase II promoter [IGI, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SLC11A1
Gene Ontology Biological Process
- L-arginine import [IDA]
- MAPK cascade [ISO]
- MHC class II biosynthetic process [IMP]
- T cell cytokine production [IMP]
- T cell proliferation involved in immune response [IMP]
- activation of protein kinase activity [IMP]
- antigen processing and presentation of peptide antigen [IMP]
- cadmium ion transmembrane transport [ISO]
- cellular cadmium ion homeostasis [ISO]
- cellular iron ion homeostasis [IMP, ISO]
- defense response to Gram-negative bacterium [IMP]
- defense response to bacterium [IMP]
- defense response to protozoan [IMP]
- divalent metal ion export [IDA]
- hydrogen ion transmembrane transport [ISO]
- inflammatory response [IMP]
- interleukin-2 production [IMP]
- interleukin-3 production [IMP]
- iron ion homeostasis [IMP]
- iron ion transport [IMP, ISO]
- mRNA stabilization [IMP]
- macrophage activation [IDA, IMP]
- manganese ion transmembrane transport [IMP]
- manganese ion transport [IMP]
- multicellular organismal iron ion homeostasis [IMP]
- negative regulation of cytokine production [IMP]
- nitrite transport [IDA]
- phagocytosis [IMP]
- positive regulation of T-helper 1 type immune response [IMP]
- positive regulation of cytokine production [IMP]
- positive regulation of dendritic cell antigen processing and presentation [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of interferon-gamma production [IMP]
- positive regulation of phagocytosis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- protein import into nucleus, translocation [IMP]
- respiratory burst [IDA]
- response to bacterium [IMP, ISO]
- response to interferon-gamma [IDA]
- response to lipopolysaccharide [IDA, IMP, ISO]
- vacuolar acidification [IMP]
- wound healing [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Lsh controls Hox gene silencing during development.
Polycomb-mediated repression and DNA methylation are important epigenetic mechanisms of gene silencing. Recent evidence suggests a functional link between the polycomb repressive complex (PRC) and Dnmts in cancer cells. Here we provide evidence that Lsh, a regulator of DNA methylation, is also involved in normal control of PRC-mediated silencing during embryogenesis. We demonstrate that Lsh, a SNF2 homolog, can associate ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SLC11A1 PCGF2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID