BAIT

HIST3H3

H3.4, H3/g, H3FT, H3t
histone cluster 3, H3
GO Process (1)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SMNDC1

SMNR, SPF30, TDRD16C
survival motor neuron domain containing 1
GO Process (4)
GO Function (2)
GO Component (4)
Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

TDRD3 is an effector molecule for arginine-methylated histone marks.

Yang Y, Lu Y, Espejo A, Wu J, Xu W, Liang S, Bedford MT

Specific sites of histone tail methylation are associated with transcriptional activity at gene loci. These methyl marks are interpreted by effector molecules, which harbor protein domains that bind the methylated motifs and facilitate either active or inactive states of transcription. CARM1 and PRMT1 are transcriptional coactivators that deposit H3R17me2a and H4R3me2a marks, respectively. We used a protein domain microarray approach to ... [more]

Mol. Cell Dec. 22, 2010; 40(6);1016-23 [Pubmed: 21172665]

Throughput

  • Low Throughput

Curated By

  • BioGRID