POU5F1
Gene Ontology Biological Process
- BMP signaling pathway involved in heart induction [IMP]
- anatomical structure morphogenesis [TAS]
- blastocyst development [ISS]
- cardiac cell fate determination [IDA]
- cell fate commitment involved in formation of primary germ layer [IMP]
- endodermal cell fate specification [IDA]
- mRNA transcription from RNA polymerase II promoter [ISS]
- negative regulation of gene silencing by miRNA [IMP]
- positive regulation of SMAD protein import into nucleus [IDA]
- positive regulation of catenin import into nucleus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of asymmetric cell division [ISS]
- regulation of gene expression [IMP]
- regulation of heart induction by regulation of canonical Wnt signaling pathway [IMP]
- regulation of methylation-dependent chromatin silencing [IDA]
- regulation of transcription, DNA-templated [IDA]
- response to wounding [IEP]
- somatic stem cell maintenance [IDA, IMP]
- transcription from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function- DNA binding [IDA]
- miRNA binding [IDA]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
- DNA binding [IDA]
- miRNA binding [IDA]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
RPL22
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5.
Long non-coding RNAs (lncRNAs) have been shown to epigenetically regulate certain genes in human cells. Here we report evidence for the involvement of an antisense lncRNA in the transcriptional regulation of the pluripotency-associated factor Oct4. When an lncRNA antisense to Oct4-pseudogene 5 was suppressed, transcription of Oct4 and Oct4 pseudogenes 4 and 5 was observed to increase. This increase correlated ... [more]
Throughput
- Low Throughput
Additional Notes
- Bait is RNA oligonucleotide, hits are proteins identified by mass spectrometry
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| POU5F1 RPL22 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID