BAIT
UCHL5
CGI-70, INO80R, UCH-L5, UCH37, RP11-101E13.2
ubiquitin carboxyl-terminal hydrolase L5
GO Process (5)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PFN1
ALS18
profilin 1
GO Process (10)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- blood coagulation [TAS]
- negative regulation of actin filament bundle assembly [IMP]
- negative regulation of actin filament polymerization [IDA]
- negative regulation of stress fiber assembly [IMP]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of ATPase activity [IDA]
- positive regulation of actin filament polymerization [IGI]
- positive regulation of epithelial cell migration [IMP]
- positive regulation of ruffle assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.
The ubiquitin C-terminal hydrolase (UCH) is a subfamily of deubiquitinating enzymes, which consists of four members: UCH-L1, UCH-L3, UCH37, and BRCA1-associated protein-1. Although there is growing evidence that UCH enzymes and human malignancies are closely correlated, there have been few studies on UCH37, especially on its interactions with other proteins. In the current study, a functional proteomic analysis was performed ... [more]
Unknown Jul. 29, 2011; 0(0); [Pubmed: 21800051]
Throughput
- High Throughput
Curated By
- BioGRID