BAIT
MAPK13
SAPK4, Serk4, RP24-313J18.2
mitogen-activated protein kinase 13
GO Process (7)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ALDOA
ALDA, GSD12, HEL-S-87p
aldolase A, fructose-bisphosphate
GO Process (16)
GO Function (8)
GO Component (9)
Gene Ontology Biological Process
- ATP biosynthetic process [IMP]
- actin filament organization [TAS]
- blood coagulation [TAS]
- carbohydrate metabolic process [TAS]
- fructose 1,6-bisphosphate metabolic process [IDA]
- fructose metabolic process [IMP]
- gluconeogenesis [TAS]
- glucose metabolic process [TAS]
- glycolytic process [IMP, TAS]
- muscle cell cellular homeostasis [IMP]
- platelet activation [TAS]
- platelet degranulation [TAS]
- protein homotetramerization [ISS]
- regulation of cell shape [IDA]
- small molecule metabolic process [TAS]
- striated muscle contraction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.
Dysfunction and loss of insulin-producing pancreatic beta cells represent hallmarks of diabetes mellitus. Here, we show that mice lacking the mitogen-activated protein kinase (MAPK) p38delta display improved glucose tolerance due to enhanced insulin secretion from pancreatic beta cells. Deletion of p38delta results in pronounced activation of protein kinase D (PKD), the latter of which we have identified as a pivotal ... [more]
Cell Jan. 23, 2009; 136(2);235-48 [Pubmed: 19135240]
Throughput
- Low Throughput
Ontology Terms
- cell line: hek-293t cell (BTO:0002181)
Curated By
- BioGRID