BAIT
BCL6
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
B-cell CLL/lymphoma 6
GO Process (9)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- negative regulation of B cell apoptotic process [NAS]
- negative regulation of cell growth [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IMP, NAS]
- positive regulation of apoptotic process [IDA]
- protein import into nucleus, translocation [IGI]
- regulation of germinal center formation [NAS]
- regulation of immune response [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DDX6
HLR2, P54, RCK
DEAD (Asp-Glu-Ala-Asp) box helicase 6
GO Process (6)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- cytoplasmic mRNA processing body assembly [IDA]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of BCL6-interacting proteins by tandem mass spectrometry.
B-cell lymphoma 6 (BCL6) is a 95-kDa nuclear phosphoprotein and member of the Pox virus zinc finger/bric-a-brac, tramtrack, broad complex (POZ/BTB) family of transcription factors. BCL6 is a transcriptional repressor required for germinal center formation, and the gene encoding it is frequently altered in diffuse large B-cell and follicular lymphomas. The dysregulation of BCL6 has therefore been implicated in lymphomagenesis. ... [more]
Mol. Cell Proteomics Dec. 01, 2005; 4(12);1898-909 [Pubmed: 16147992]
Throughput
- Low Throughput
Curated By
- BioGRID