BAIT
BCL6
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
B-cell CLL/lymphoma 6
GO Process (9)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- negative regulation of B cell apoptotic process [NAS]
- negative regulation of cell growth [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IMP, NAS]
- positive regulation of apoptotic process [IDA]
- protein import into nucleus, translocation [IGI]
- regulation of germinal center formation [NAS]
- regulation of immune response [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DROSHA
ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L, RNASEN
drosha, ribonuclease type III
GO Process (6)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of BCL6-interacting proteins by tandem mass spectrometry.
B-cell lymphoma 6 (BCL6) is a 95-kDa nuclear phosphoprotein and member of the Pox virus zinc finger/bric-a-brac, tramtrack, broad complex (POZ/BTB) family of transcription factors. BCL6 is a transcriptional repressor required for germinal center formation, and the gene encoding it is frequently altered in diffuse large B-cell and follicular lymphomas. The dysregulation of BCL6 has therefore been implicated in lymphomagenesis. ... [more]
Mol. Cell Proteomics Dec. 01, 2005; 4(12);1898-909 [Pubmed: 16147992]
Throughput
- Low Throughput
Curated By
- BioGRID