BAIT
MME
CALLA, CD10, NEP, SFE
membrane metallo-endopeptidase
GO Process (12)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- angiotensin maturation [TAS]
- beta-amyloid metabolic process [ISS]
- cellular protein metabolic process [TAS]
- cellular response to UV-A [IDA]
- cellular response to UV-B [IDA]
- cellular response to cytokine stimulus [IDA]
- creatinine metabolic process [IMP]
- kidney development [IEP]
- peptide metabolic process [ISS]
- proteolysis [IDA]
- replicative senescence [IEP]
- sensory perception of pain [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFB4
B15, CI-B15
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
GO Process (5)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells.
CD10 is an approximately 100 kDa transmembrane metallo-endopeptidase. CD10 is strongly expressed by normal prostate epithelium. While only 30% of primary prostate tumors express CD10, it is strongly expressed by most lymph node metastases. The function of CD10 and the interaction between CD10 and other cellular proteins in prostate cancer (CaP) is not well defined. Cellular context may ultimately determine ... [more]
Prostate May. 15, 2007; 67(7);714-21 [Pubmed: 17342744]
Throughput
- High Throughput
Ontology Terms
- disease: prostate cancer (DOID:10283)
- cell line: lncap-c42b4 cell (BTO:0002998)
Curated By
- BioGRID