BAIT

CDC27A

AT3G16320
cell division cycle protein 27-A
GO Process (3)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

CYCB1;1

CYC1, CYCB1, CYCLIN 1, CYCLIN B1;1, F6G17.140, F6G17_140, AT4G37490
cyclin-B1-1
GO Process (3)
GO Function (2)
GO Component (1)
Arabidopsis thaliana (Columbia)

Biochemical Activity (Ubiquitination)

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

Overexpression of the Arabidopsis anaphase promoting complex subunit CDC27a increases growth rate and organ size.

Rojas CA, Eloy NB, Lima Mde F, Rodrigues RL, Franco LO, Himanen K, Beemster GT, Hemerly AS, Ferreira PC

The Anaphase Promoting Complex (APC) controls CDK activity by targeting the ubiquitin-dependent proteolysis of S-phase and mitosis-promoting cyclins. Here, we report that the ectopic expression of the Arabidopsis CDC27a, an APC subunit, accelerates plant growth and results in plants with increased biomass production. CDC27a overexpression was associated to apical meristem restructuration, protoplasts with higher (3)H-thimidine incorporation and altered cell-cycle marker ... [more]

Plant Mol. Biol. Oct. 01, 2009; 71(3);307-18 [Pubmed: 19629716]

Throughput

  • Low Throughput

Additional Notes

  • As part of immunoprecipitated APC complex. Mixed with human E1 and E2.

Curated By

  • BioGRID