BAIT
NCOA3
ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP, RP5-1049G16.3
nuclear receptor coactivator 3
GO Process (10)
GO Function (9)
GO Component (4)
Gene Ontology Biological Process
- androgen receptor signaling pathway [NAS]
- cellular response to hormone stimulus [IBA]
- histone acetylation [IDA]
- intracellular receptor signaling pathway [IBA]
- positive regulation of gene expression [IMP]
- positive regulation of keratinocyte differentiation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription, DNA-templated [NAS]
- receptor transactivation [TAS]
- regulation of RNA biosynthetic process [IMP]
Gene Ontology Molecular Function- androgen receptor binding [NAS]
- histone acetyltransferase activity [IDA]
- ligand-dependent nuclear receptor binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IBA]
- nuclear hormone receptor binding [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- thyroid hormone receptor binding [NAS]
- transcription coactivator activity [IDA, IMP, NAS]
- androgen receptor binding [NAS]
- histone acetyltransferase activity [IDA]
- ligand-dependent nuclear receptor binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IBA]
- nuclear hormone receptor binding [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- thyroid hormone receptor binding [NAS]
- transcription coactivator activity [IDA, IMP, NAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
ANXA2
ANX2, ANX2L4, CAL1H, HEL-S-270, LIP2, LPC2, LPC2D, P36, PAP-IV
annexin A2
GO Process (7)
GO Function (7)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.
We report our initial efforts in the analysis of endogenous nuclear receptor coactivator complexes as a research bridging strand of the Nuclear Receptor Signaling Atlas (NURSA) (www.NURSA.org). A proteomic approach is used to systematically isolate a variety of coactivator complexes using HeLa cells as a model cell line and to identify the coactivator-associated proteins with mass spectrometry. We have isolated ... [more]
Mol. Endocrinol. Oct. 01, 2005; 19(10);2451-65 [Pubmed: 16051665]
Throughput
- Low Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID