STAU1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PPP1CA
Gene Ontology Biological Process
- branching morphogenesis of an epithelial tube [ISO]
- circadian regulation of gene expression [ISO, ISS]
- entrainment of circadian clock by photoperiod [ISO, ISS]
- lung development [ISO]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- protein dephosphorylation [IDA, ISO]
- regulation of circadian rhythm [ISO, ISS]
- regulation of glycogen biosynthetic process [IDA]
- regulation of glycogen catabolic process [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- PTW/PP1 phosphatase complex [ISO, ISS]
- cytoplasm [IDA, ISO]
- cytosol [TAS]
- dendritic spine [IDA]
- extracellular vesicular exosome [ISO]
- glycogen granule [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- perikaryon [IDA]
- plasma membrane [ISO]
- protein phosphatase type 1 complex [IDA]
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Characterization of Staufen 1 ribonucleoprotein complexes.
In Drosophila oocytes and neuroblasts, the double-stranded RNA binding protein Staufen assembles into ribonucleoprotein particles, which mediate cytoplasmic mRNA trafficking and translation. Two different mammalian orthologues also appear to reside in distinct RNA-containing particles. To date, relatively little is known about the molecular composition of Staufen-containing ribonucleoprotein complexes. Here, we have used a novel one-step affinity purification protocol to identify ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID