ARRDC3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ITGB4
Gene Ontology Biological Process
- amelogenesis [IMP]
- autophagy [IMP]
- cell adhesion [NAS]
- cell junction assembly [TAS]
- cell motility [IMP]
- cell-matrix adhesion [IMP]
- digestive tract development [IMP]
- extracellular matrix organization [TAS]
- hemidesmosome assembly [IDA, IMP, TAS]
- mesodermal cell differentiation [IEP]
- nail development [IMP]
- renal system development [IMP]
- response to wounding [IDA]
- skin development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4.
Large-scale genetic analyses of human tumor samples have been used to identify novel oncogenes, tumor suppressors and prognostic factors, but the functions and molecular interactions of many individual genes have not been determined. In this study we examined the cellular effects and molecular mechanism of the arrestin family member, ARRDC3, a gene preferentially lost in a subset of breast cancers. ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID