ESRRG
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NR0B1
Gene Ontology Biological Process
- adrenal gland development [IMP]
- gene expression [TAS]
- gonad development [IMP]
- hypothalamus development [NAS]
- intracellular receptor signaling pathway [IDA, NAS]
- male gonad development [IMP]
- negative regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of sequence-specific DNA binding transcription factor activity [IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- pituitary gland development [NAS]
- protein localization [IDA]
- steroid biosynthetic process [IDA]
- transcription initiation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function- AF-2 domain binding [IPI]
- DNA binding [IDA]
- DNA hairpin binding [IDA]
- RNA binding [IDA]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, NAS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- steroid hormone receptor binding [IPI]
- transcription corepressor activity [IMP]
- transcription factor binding [IPI]
- AF-2 domain binding [IPI]
- DNA binding [IDA]
- DNA hairpin binding [IDA]
- RNA binding [IDA]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, NAS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- steroid hormone receptor binding [IPI]
- transcription corepressor activity [IMP]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
High throughput analysis of protein-protein interactions is an important sector of hypothesis-generating research. Using an improved and automated version of the yeast two-hybrid system, we completed a large interaction screening project with a focus on nuclear receptors and their cofactors. A total of 425 independent yeast two-hybrid cDNA library screens resulted in 6425 potential interacting protein fragments involved in 1613 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NR0B1 ESRRG | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2738667 | |
| NR0B1 ESRRG | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID