BAIT
NR3C2
MCR, MLR, MR, NR3C2VIT
nuclear receptor subfamily 3, group C, member 2
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PROX1
prospero homeobox 1
GO Process (47)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
- aorta smooth muscle tissue morphogenesis [ISS]
- atrial cardiac muscle tissue morphogenesis [ISS]
- brain development [IEP]
- cerebellar granule cell differentiation [ISS]
- dentate gyrus development [ISS]
- dorsal spinal cord development [ISS]
- embryonic retina morphogenesis in camera-type eye [IEP]
- endocardium formation [ISS]
- hepatocyte differentiation [IEP]
- kidney development [IEP]
- lens development in camera-type eye [IEP]
- lens fiber cell morphogenesis [IEP]
- liver development [IEP]
- lung development [IEP]
- lymphangiogenesis [IDA]
- lymphatic endothelial cell differentiation [IDA]
- negative regulation of bile acid biosynthetic process [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- negative regulation of viral genome replication [IDA]
- neural tube development [ISS]
- neuronal stem cell maintenance [ISS]
- olfactory placode formation [ISS]
- optic placode formation involved in camera-type eye formation [ISS]
- otic placode formation [ISS]
- pancreas development [IEP]
- positive regulation of cell cycle [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- positive regulation of endothelial cell migration [IDA]
- positive regulation of endothelial cell proliferation [IDA]
- positive regulation of forebrain neuron differentiation [ISS]
- positive regulation of heart growth [ISS]
- positive regulation of neural precursor cell proliferation [ISS]
- positive regulation of sarcomere organization [ISS]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of circadian rhythm [IMP]
- regulation of gene expression [IDA]
- regulation of transcription involved in lymphatic endothelial cell fate commitment [IMP]
- retina morphogenesis in camera-type eye [ISS]
- skeletal muscle thin filament assembly [ISS]
- venous blood vessel morphogenesis [ISS]
- ventricular cardiac muscle tissue morphogenesis [ISS]
- ventricular cardiac myofibril assembly [ISS]
- ventricular septum morphogenesis [ISS]
Gene Ontology Molecular Function- DBD domain binding [IPI]
- DNA binding [IMP]
- LBD domain binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- core promoter sequence-specific DNA binding [ISS]
- ligand-dependent nuclear receptor binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IC]
- transcription corepressor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- DBD domain binding [IPI]
- DNA binding [IMP]
- LBD domain binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- core promoter sequence-specific DNA binding [ISS]
- ligand-dependent nuclear receptor binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IC]
- transcription corepressor activity [IDA]
- transcription regulatory region DNA binding [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
High throughput analysis of protein-protein interactions is an important sector of hypothesis-generating research. Using an improved and automated version of the yeast two-hybrid system, we completed a large interaction screening project with a focus on nuclear receptors and their cofactors. A total of 425 independent yeast two-hybrid cDNA library screens resulted in 6425 potential interacting protein fragments involved in 1613 ... [more]
Mol. Cell Proteomics Feb. 01, 2005; 4(2);205-13 [Pubmed: 15604093]
Throughput
- Low Throughput
Curated By
- BioGRID