BAIT
DMRT2
Terra
doublesex and mab-3 related transcription factor 2
GO Process (6)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
IQGAP1
AA682088, D7Ertd237e, D7Ertd257e, mKIAA0051
IQ motif containing GTPase activating protein 1
GO Process (12)
GO Function (9)
GO Component (21)
Gene Ontology Biological Process
- cellular response to calcium ion [ISO]
- cellular response to epidermal growth factor stimulus [IMP, ISO]
- cellular response to fibroblast growth factor stimulus [IMP]
- cellular response to platelet-derived growth factor stimulus [IMP]
- epidermal growth factor receptor signaling pathway [IMP, ISO]
- fibroblast growth factor receptor signaling pathway [IMP]
- negative regulation of dephosphorylation [IGI]
- neuron projection extension [ISO]
- platelet-derived growth factor receptor signaling pathway [IMP]
- positive regulation of protein kinase activity [IMP, ISO]
- positive regulation of protein serine/threonine kinase activity [ISO]
- regulation of cytokine production [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- axon [ISO]
- cell junction [ISO]
- cell leading edge [IGI]
- cell-cell junction [IDA]
- cytoplasm [IDA, ISO]
- cytoplasmic ribonucleoprotein granule [ISO]
- extracellular vesicular exosome [ISO]
- extrinsic component of cytoplasmic side of plasma membrane [ISO]
- focal adhesion [ISO]
- growth cone [ISO]
- lateral plasma membrane [IDA]
- membrane [IDA]
- microtubule [ISO]
- microtubule cytoskeleton [ISO]
- midbody [ISO]
- neuron projection [IGI, ISO]
- nucleoplasm [ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- ribonucleoprotein complex [IDA, IGI]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TERRA transcripts are bound by a complex array of RNA-binding proteins.
Telomeres are transcribed from the telomeric C-rich strand, giving rise to UUAGGG repeat-containing telomeric transcripts or TERRA, which are novel structural components of telomeres. TERRA abundance is highly dependent on developmental status (including nuclear reprogramming), telomere length, cellular stresses, tumour stage and chromatin structure. However, the molecular mechanisms and factors controlling TERRA levels are still largely unknown. In this study, ... [more]
Nat Commun Oct. 27, 2010; 1(0);33 [Pubmed: 20975687]
Throughput
- Low Throughput
Curated By
- BioGRID