BAIT
TUBG1
1500010O08Rik, AI451582, AI503389, Tubg, RP23-440M18.7
tubulin, gamma 1
GO Process (3)
GO Function (2)
GO Component (17)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [IDA]
- cell leading edge [IDA]
- centriole [IDA]
- centrosome [IDA, ISO]
- ciliary basal body [IDA]
- cilium [IDA]
- condensed nuclear chromosome [IDA]
- cytoplasm [IDA, ISO]
- cytoplasmic microtubule [IDA]
- gamma-tubulin complex [ISO]
- microtubule organizing center [TAS]
- nonmotile primary cilium [IDA]
- pericentriolar material [IDA]
- polar microtubule [ISO]
- recycling endosome [ISO]
- spindle microtubule [IDA]
- spindle pole [TAS]
Mus musculus
PREY
AIFM1
AIF, CMT2D, CMTX4, COWCK, COXPD6, NADMR, NAMSD, PDCD8, RP3-438D16.2
apoptosis-inducing factor, mitochondrion-associated, 1
GO Process (9)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- DNA catabolic process [TAS]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [IMP]
- chromosome condensation [TAS]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- mitochondrial respiratory chain complex I assembly [IMP]
- neuron differentiation [IDA]
- positive regulation of apoptotic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID