BAIT
ZWINT
2010007E07Rik, 2600001N01Rik, D10Ertd749e, Zwint-1
ZW10 interactor
GO Process (3)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NUP62
IBSN, SNDI, p62
nucleoporin 62kDa
GO Process (23)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cell death [IMP, ISS]
- cell surface receptor signaling pathway [IDA, ISS, NAS]
- cytokine-mediated signaling pathway [TAS]
- glucose transport [TAS]
- hexose transport [TAS]
- hormone-mediated signaling pathway [NAS]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- negative regulation of apoptotic process [IDA, ISS]
- negative regulation of cell proliferation [IDA, ISS]
- negative regulation of programmed cell death [IDA, ISS]
- nucleocytoplasmic transport [NAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA, ISS]
- positive regulation of epidermal growth factor receptor signaling pathway [NAS]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- regulation of Ras protein signal transduction [NAS]
- regulation of glucose transport [TAS]
- regulation of signal transduction [NAS]
- small molecule metabolic process [TAS]
- transcription, DNA-templated [IDA, ISS]
- transmembrane transport [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID