BAIT
RHOA
Arha, Arha1, Arha2
ras homolog gene family, member A
GO Process (44)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
- GTP catabolic process [IDA, ISO]
- Rho protein signal transduction [TAS]
- actin cytoskeleton organization [IDA]
- androgen receptor signaling pathway [IDA]
- apical junction assembly [IDA, ISO]
- apolipoprotein A-I-mediated signaling pathway [ISO]
- cell adhesion [IMP]
- cell differentiation [IDA]
- cell morphogenesis [IGI]
- cell-matrix adhesion [IDA]
- cerebral cortex cell migration [IMP]
- cleavage furrow formation [ISO]
- cytoskeleton organization [IMP]
- forebrain radial glial cell differentiation [IMP]
- integrin-mediated signaling pathway [TAS]
- negative chemotaxis [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of cell death [ISO]
- negative regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of neuron differentiation [ISO]
- ossification involved in bone maturation [IMP]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron apoptotic process [ISO]
- positive regulation of neuron differentiation [ISO]
- positive regulation of podosome assembly [IGI]
- positive regulation of smooth muscle contraction [ISO]
- positive regulation of stress fiber assembly [ISO]
- regulation of calcium ion transport [ISO]
- regulation of cell migration [ISO]
- regulation of dendrite development [ISO]
- regulation of neural precursor cell proliferation [IMP]
- regulation of neuron projection development [IDA]
- regulation of osteoblast proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to drug [ISO]
- skeletal muscle tissue development [IDA]
- spindle assembly involved in mitosis [ISO]
- stress fiber assembly [IDA]
- stress-activated protein kinase signaling cascade [ISO]
- trabecula morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RHOA
ARH12, ARHA, RHO12, RHOH12
ras homolog family member A
GO Process (29)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- GTP catabolic process [TAS]
- Rho protein signal transduction [TAS]
- actin cytoskeleton organization [TAS]
- apical junction assembly [IMP]
- apolipoprotein A-I-mediated signaling pathway [IMP]
- axon guidance [TAS]
- blood coagulation [TAS]
- cleavage furrow formation [IDA]
- negative chemotaxis [IMP]
- negative regulation of axonogenesis [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- ossification involved in bone maturation [ISS]
- phosphatidylinositol-mediated signaling [TAS]
- platelet activation [TAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IEP]
- positive regulation of NF-kappaB import into nucleus [NAS]
- positive regulation of axonogenesis [TAS]
- positive regulation of cytokinesis [IMP]
- positive regulation of neuron differentiation [IMP]
- positive regulation of stress fiber assembly [IDA]
- regulation of axonogenesis [TAS]
- regulation of cell migration [IMP]
- regulation of osteoblast proliferation [ISS]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- spindle assembly involved in mitosis [IMP]
- substantia nigra development [IEP]
- trabecula morphogenesis [ISS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID