BAIT
NIPBL
Idn3
Nipped-B homolog (Drosophila)
GO Process (34)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- brain development [ISO]
- cellular protein localization [ISO]
- cellular response to DNA damage stimulus [ISO]
- cellular response to X-ray [ISO]
- cognition [ISO]
- developmental growth [ISO]
- ear morphogenesis [ISO]
- embryonic cranial skeleton morphogenesis [IMP]
- embryonic digestive tract morphogenesis [ISO]
- embryonic forelimb morphogenesis [ISO]
- embryonic viscerocranium morphogenesis [IMP]
- external genitalia morphogenesis [ISO]
- eye morphogenesis [ISO]
- face morphogenesis [ISO]
- fat cell differentiation [IMP]
- forelimb morphogenesis [ISO]
- gall bladder development [ISO]
- heart development [IMP]
- heart morphogenesis [ISO]
- maintenance of mitotic sister chromatid cohesion [ISO]
- mitotic sister chromatid cohesion [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- outflow tract morphogenesis [ISO]
- positive regulation of histone deacetylation [ISO]
- positive regulation of multicellular organism growth [IMP]
- positive regulation of ossification [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of developmental growth [ISO]
- regulation of embryonic development [ISO]
- regulation of hair cycle [ISO]
- sensory perception of sound [ISO]
- stem cell maintenance [IMP]
- uterus morphogenesis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KPNA1
IPOA5, NPI-1, RCH2, SRP1
karyopherin alpha 1 (importin alpha 5)
GO Process (10)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [TAS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cytokine-mediated signaling pathway [TAS]
- intracellular transport of virus [TAS]
- positive regulation of protein import into nucleus [ISS]
- regulation of DNA recombination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID