BAIT
DYNLL1
Dlc8, Dnclc1, Pin
dynein light chain LC8-type 1
GO Process (5)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
TLK2
HsHPK, PKU-ALPHA
tousled-like kinase 2
GO Process (9)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- cellular response to gamma radiation [IDA]
- chromosome segregation [IMP]
- intracellular signal transduction [IDA]
- negative regulation of autophagy [NAS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- peptidyl-serine phosphorylation [IDA]
- protein phosphorylation [IDA]
- regulation of chromatin assembly or disassembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID