BAIT
PLK2
Snk
polo-like kinase 2
GO Process (17)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO]
- Rap protein signal transduction [ISO]
- Ras protein signal transduction [ISO]
- long term synaptic depression [ISO]
- long-term synaptic potentiation [ISO]
- memory [IMP]
- mitotic cell cycle [IMP]
- mitotic cell cycle checkpoint [IMP]
- mitotic spindle organization [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of dendritic spine development [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of protein binding [ISO]
- protein phosphorylation [IDA, ISO]
- regulation of centriole replication [ISO]
- regulation of synaptic plasticity [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PLK2
SNK, hPlk2, hSNK
polo-like kinase 2
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- Rap protein signal transduction [ISS]
- Ras protein signal transduction [ISS]
- long term synaptic depression [ISS]
- long-term synaptic potentiation [ISS]
- memory [ISS]
- mitotic cell cycle checkpoint [ISS]
- mitotic spindle organization [IDA]
- negative regulation of apoptotic process [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- protein phosphorylation [IDA]
- regulation of centriole replication [IDA, IMP]
- regulation of synaptic plasticity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID