BAIT
MAD2L2
2310033C13Rik, G1-453-4, MAD2B, REV7, repro22, RP23-139J21.8
MAD2 mitotic arrest deficient-like 2
GO Process (15)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- DNA damage response, signal transduction resulting in transcription [ISO]
- actin filament organization [ISO]
- double-strand break repair [ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of cell-cell adhesion mediated by cadherin [ISO]
- negative regulation of epithelial to mesenchymal transition [ISO]
- negative regulation of mitotic anaphase-promoting complex activity [ISO]
- negative regulation of protein catabolic process [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription by competitive promoter binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription regulatory region DNA binding [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of cell growth [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ALDH3A2
ALDH10, FALDH, SLS
aldehyde dehydrogenase 3 family, member A2
GO Process (7)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID