BAIT
SLC25A4
AU019225, Ant1
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
GO Process (9)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- apoptotic mitochondrial changes [IGI]
- ion transmembrane transport [ISO]
- negative regulation of cardiac muscle cell apoptotic process [ISO]
- negative regulation of mitochondrial membrane permeability involved in apoptotic process [ISO]
- negative regulation of necroptotic process [ISO]
- nucleotide transmembrane transport [ISO]
- positive regulation of cell growth involved in cardiac muscle cell development [ISO]
- positive regulation of oxidative phosphorylation uncoupler activity [ISO]
- purine nucleoside transmembrane transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BCLAF1
BTF, bK211L9.1
BCL2-associated transcription factor 1
GO Process (7)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [TAS]
- negative regulation of transcription, DNA-templated [IDA, TAS]
- positive regulation of DNA-templated transcription, initiation [IMP]
- positive regulation of apoptotic process [IDA]
- positive regulation of intrinsic apoptotic signaling pathway [IMP]
- positive regulation of response to DNA damage stimulus [IMP]
- regulation of DNA-templated transcription in response to stress [IMP]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID