BAIT
RACGAP1
AI227039, AI327394, Band25, GTPase, MgcRacGAP, gtl11, mKIAA1478
Rac GTPase-activating protein 1
GO Process (9)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
- actomyosin contractile ring assembly [ISO]
- cytokinesis, initiation of separation [ISO]
- embryo development [IMP]
- mitotic cytokinesis [ISO]
- mitotic spindle midzone assembly [ISO]
- positive regulation of GTPase activity [ISO]
- positive regulation of cytokinesis [ISO]
- regulation of attachment of spindle microtubules to kinetochore [ISO]
- sulfate transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SH3KBP1
CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, RP11-345L8.1
SH3-domain kinase binding protein 1
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID